This document provides:

a)      

a review of radioisotope labelling methods that can be used for nanomaterials;

b)      

the advantages and disadvantages of each radioisotope labelling method;

c)       

information on the selection of a matched pair of nanomaterial and radioisotope labelling method to ensure the in vivo integrity of radioisotope-labelled nanomaterials or the stability of their performance.